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breast cancer

Etirinotecan Pegol Active in Patients With Previously Treated Metastatic Breast Cancer

Etirinotecan pegol is a topoisomerase-I inhibitor designed to provide prolonged tumor cell exposure to the active metabolite of irinotecan. In a phase II study reported in The Lancet Oncology, Ahmad Awada, MD, of Jules Bordet Institute, Université Libre de Bruxelles, and colleagues examined...

breast cancer

Long-Term Results of UK START Trials Support Hypofractionated Adjuvant Radiotherapy in Invasive Early Breast Cancer

The 5-year results of the UK Standardisation of Breast Radiotherapy (START) trials suggested that lower total doses of radiotherapy delivered in fewer, larger doses were at least as safe and effective as the historical standard regimen of 50 Gy in 25 fractions as adjuvant therapy for early breast...

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